In contrast, the addition of anti-PS targeting antibodies either alone or in combination with anti-PD-1 resulted in the greatest overall survival (40% survival compared to 10% survival of both DPX-R9F/CPA/isotype or DPX-R9F/CPA/anti-PD-1/isotype), and moderately reduced tumour burden compared to other groups (147.6mm3 for DPX/CPA/anti-PS/anti-PD-1 compared to 303.4mm3 compared to the DPX-R9F/CPA/anti-PS, and 569.4 mm3 for DPX-R9F/CPA/anti-PD-1 at day study day 50). Here, PDCD1 is linked to neoplasm.