The expression of BCL2L1 was also high in TI-Tregs in human hepatocellular carcinoma (HCC scRNAseq dataset GSE98638)19 (Supplementary Fig. 1d, shown as Napierian log fold-change versus percent difference compared to PB-counterparts), as well as in mouse MC38 colon adenocarcinoma (Fig. 1b and Supplementary Table 1, here the comparison is to spleen Tregs shown as log2 (n + 1)-transformed data). This evidence concerns the gene BCL2L1 and colon adenocarcinoma.