In accordance with our infarct core-to-border axis (punch positions 5–8) analysis, we found that seven of the KLF family of TFs (KLF2–4, 6–8, and 12) were significantly depleted in glutamatergic neurons at the glial scar in the stroke hemisphere (Fig. 8d, right; KLF4 and KLF7 shown). This evidence concerns the gene KLF4 and stroke disorder.