ENG and hepatocellular carcinoma: We found that the anti-CD105 CAR-T cells had potent cytotoxicity against HCC cells (Bel7404, HepG2, and SMMC7721) that expressed high levels of CD105 and CD105-positive HUVEC cells, but little cytotoxicity against CD105-low expressing MHCC97H cells, whereas the Utd, Mock, and anti-CD19 CAR-T cells had low or little cytotoxicity against such HCC cells.