On the other hand, the normal expression of hsa_circRNA_103809 shows an inhibitory effect on tumor growth, while the decreased expression of hsa_circRNA_103809 in colorectal cancer (CRC) eliminates its inhibitory effect and can promote the proliferation and migration of CRC cells through the miR532-3p/FOXO4 axis19. This evidence concerns the gene FOXO4 and neoplasm.