However, the backward stepwise regression model showed that dp-ucMGP was not an independent determinant of CAC or AVC; instead determinants of CAC included older age, and diabetes (pseudo r2 = 0.45) and determinants of AVC were older age, lower albumin and beta-blocker use (pseudo r2 = 0.29) (Table 3). The gene discussed is ALB; the disease is diabetes mellitus.