Consistently, restoration of ΔNp63α completely rescued TβRI-induced alterative expression of desmoplakin, Par3, Integrinβ1, E-cadherin, Vimentin, and Twist1 in HCC1806 and HCC-1937 cells (S5H and S5I Fig). The gene discussed is TGFBR1; the disease is hepatocellular carcinoma.