A region on the edge of this super-enhancer (mm9 coordinates chr15:85,473,689–85,478,592, published mm10 coordinates chr15: 85,643,259–85,648,162) was recently indeed associated with Wnt7b, albeit not in the mammary gland but in a mouse model for hair-follicle derived skin tumors, and based on strain-specific polymorphisms rather than on having been shown to directly regulate Wnt7b expression [14]. Here, WNT7B is linked to skin neoplasm.