CREB1 and stroke disorder: We further report that neuroplasticity (Tau, GAP-43), synaptogenesis (SYN, PSD-95), angiogenesis (VEGF, Ang-1, Ang-2), and neural plasticity regulation (TrkB, CREB, BDNF, NGF) were associated with improved neurorehabilitation by both exercise and ischemic conditioning after stroke, with further intermittent increases with ischemic conditioning.