Finally, the GWAS catalogue [59] reveals potential associations of C1ORF112 with amyotrophic lateral sclerosis, acne, epigenetic age acceleration, venous thromboembolism, and blood protein levels (https://www.ebi.ac.uk/gwas/genes/C1orf112), and these findings open further avenues for future studies. This evidence concerns the gene FIRRM and acne.