Mutations in the human LMNA gene cause a group of diseases called laminopathies, including Hutchinson–Gilford progeria syndrome (HGPS), an extremely rare genetic disorder with an estimated prevalence of 1 in 18 million people (www.progeriaresearch.org) that is characterized by premature aging.2 This evidence concerns the gene LMNA and Hutchinson-Gilford progeria syndrome.