That study showed that patients with the CC IFNL3 genotype had a greater likelihood of experiencing spontaneous resolution, while patients with the non-CC IFNL3 genotype were more likely to develop chronic hepatitis C. In our previous study, we studied whether haplotypes of the human leukocyte antigen (HLA) and killer cell immunoglobulin-like receptor (KIR) improved the predictive capacity of the IFNL3 genotype and found that different combinations of these genes (HLA-B44, HLA-C12, and KIR3DS1), together with the IFNL3 genotype, increased the classification accuracy of HCV outcome. Here, IFNL3 is linked to chronic hepatitis C virus infection.