In addition, Ma et al. found neutrophil polarization during myocardial infarction (MI) and suggested that lipopolysaccharide (LPS)/interferon gamma (INF-γ) stimulates the polarization of blood peripheral neutrophils to proinflammatory N1, whereas IL-4 triggers the polarization of anti-inflammatory N2 similar to macrophage phenotypes [35]. The gene discussed is IL4; the disease is myocardial infarction.