For example, RBFOX2, SND1, and FMR1 binding sites were frequently disrupted by ASD-associated variants, consistent with the roles of these proteins as revealed by previous studies.78–80 Notably, again, the “sequence & structure” HAR group showed relatively higher levels of enrichment for these psychiatric disorder-associated variants than the other HAR groups. The gene discussed is RBFOX2; the disease is psychiatric disorder.