LTA and autoimmune thyroid disease: Functional exploration of the distinct markers (193 proteins, Supplementary Data 10 and 11) unique to the ΔCbpD-infected spleens showed enrichment of several cellular responses, including apoptosis-induced DNA fragmentation and autoimmune thyroid disease by the upregulated proteins, and synthesis of leukotrienes (LT) and eoxins (EX) and engulfment of apoptotic cells by the downregulated proteins (Fig. 4i).