PHGDH and type 2 diabetes mellitus: For CpGs that have been reported in other studies that were not replicated in our meta-analysis, we found that hypermethylation in cg11024682 (SREBF1) and hypomethylation in cg11376147 (SLC43A1), cg18181703 (SOCS3) and cg14476101 (PHGDH), were nominally associated with T2D cases versus controls, in agreement with the original studies [22, 23, 25].