In total, 4/6 differentially methylated CpGs remained associated with T2D at p < 1.3 × 10–7 in the random-effect analysis: cg19693031 (TXNIP), cg00144180 (HDAC4), cg16765088 (near SYNM) and cg24704287 (near MIR23A). This evidence concerns the gene TXNIP and type 2 diabetes mellitus.