Remarkably, the median expression levels of SRRM4 were significantly lower in tumors from all tissues, with the exception of liver that had median expression of 0.0 in both tumor and normal samples (p < 0.001; Wilcoxon–Mann–Whitney test; Fig 2A, S1 Data; details of the statistical tests are found in the Methods section under “Statistical information”). This evidence concerns the gene SRRM4 and neoplasm.