He et al. found that the TT genotype of HIF1A was common in small cell carcinoma (OR=1.73, 95% CI: 1.05-2.84) and that among passive smokers, rs2057482 TT carriers were 2.195 times more likely to develop lung cancer compared to CC carriers (95% CI: 1.038-4.463). The gene discussed is HIF1A; the disease is lung cancer.