CEBPZ and acute myeloid leukemia: These include APL with its characteristic translocation 15;17 [t(15;17) (q22,q21)]; inversion 16 [inv 16(p13; q22)] or t(16;16) (p13;q22) and t(8;21)(q22;q22,), together referred to as CBF AML; diploid karyotype (about 40–50% of patients); complex karyotype (three or more chromosomal abnormalities); others.