KIF16B and triple-negative breast carcinoma: To compare the impacts of altered kinesin function in cells with or without CIN, we measured cell proliferation in both stable, diploid breast epithelial MCF10A cells and the chromosomally unstable triple-negative breast cancer (TNBC) cell lines MDA-MB-231, MDA-MB-468, and HCC180615 following knockdown (KD) of kinesin motor proteins.