YTHDF1 and hepatocellular carcinoma: To further determine whether YTHDF1 promoted HCC malignancy under hypoxia by promoting autophagy, YTHDF1-overexpressing cells were treated with the autophagy inhibitor 3-methyladenine (3-MA, a PI3K and PtdIns3K inhibitor) (Fig. 3p and Supplementary Fig. S4o).