Figure 4b summarizes the findings that the percent area of CR3 immunoreactivity is increased from sham in the ipsilateral hemisphere after ischemic stroke similarly among the sex groups (region: F(3,60) = 16.35, p < 0.0001; sex: F(2, 45) = 0.05, p > 0.05; interaction: F(6,60) = .89, p > 0.05). This evidence concerns the gene CRIPTO3 and ischemic stroke.