Interrogation of CCLE database revealed that FZD5 is positively correlated with epithelial-related factors CDH1 (E-cadherin), OCLN (Occludin), EPCAM and ELF3, while negatively correlated with mesenchymal-related factors VIM (Vimentin), SNAI2 (Slug), ZEB1 and ZEB2 in 37 gastric cancer cell lines (Fig. 1a). Here, CDH1 is linked to gastric cancer.