When stratified by four stages of hemoglobin levels, there were significant differences in age, gender,diabetes, education level,income, UACR levels,blood pressure, BMI,albumin, ACR,eGFR; The adjusted prevalence of hemoglobin (Hb) less than 100 g/L was 10.3% (95% confidence interval [CI]: 9.9,11.4%) and showed an increased trend through reduced eGFR levels from 4.0% (95%CI:2.3,5.9%) in the 45-60 ml/min/1.73m2 group to 23.4% (95%CI:20.5,26.2%) in the 15–29 ml/min/1.73m2 group. This evidence concerns the gene GSTM1 and diabetes mellitus.