For example, in a study of 48 participants with cirrhosis and nonalcoholic fatty liver disease, Niu et al. revealed the association of five plasma proteins (DPP4, ANPEP, TGFBI, PIGR and APOE) with liver enzymes through a global correlation map of clinical and proteomic data, implying their associations with cirrhosis and nonalcoholic fatty liver disease [12]. Here, APOE is linked to Cirrhosis.