UMOD and acute kidney injury: Nephron compartment-enriched proteins nephrin (glomerulus), SLC22A2, cubilin (proximal tubule), calbindin (distal tubule) and uromodulin (distal tubule & Loop of Henle) were selected to potentially address the need for the differentiation between prerenal AKI and ATN (clinical need IV) and facilitate localization of kidney damage.