The 3' fusions TANC2-PRKCA, SLC44A1-PRKCA, and GGA2-PRKCB, found in lung squamous cell carcinoma (LUSC), papillary glioneuronal tumors (PGNT), and low-grade glioma (LGG), respectively, were selected for biochemical analysis (Fig. 2A) (34, 35, 36, 37). Here, PRKCB is linked to low grade glioma.