NLRP6 and infection: In the present study, we elucidate the impact of different gut microbiota composition by using two different mouse strains from WT (C57/bl6) and NLRP6 (Nlrp6-/-) mice in a model of oral infection by B. abortus. Our results suggest that mice deficient in NLRP6 were more resistant to B. abortus infection since there was no disruption in intestinal barrier after infection.