The PlGF level (p = 0.004) was the only marker that was significantly decreased in the preeclampsia‐positive patients, resulting in more profoundly increased calculated ratios, including sFlt‐1/PlGF (p < 0.001), GlyFn/PlGF (p = 0.002), and PAPP‐A2/PlGF (p = 0.003). The gene discussed is PAPPA2; the disease is preeclampsia.