In this work, we aimed to evaluate the predictive values of: (1) the known markers of sFlt‐1 and PlGF, and (2) PAPP‐A2, GlyFn, TM, tissue plasminogen activator inhibitor complex (tPAI‐C), complement factors C1q, B, and H, and renal function markers including UA, BUN, Cre, and Cysc, in a prospective study with Chinese pregnant women who were suspected to develop preeclampsia. The gene discussed is THBD; the disease is preeclampsia.