Interestingly, the amino acid sequences of the 2 CSF expanded TCR β clonotypes (CASSQPLAGDYEQYF at positions 6–9 and CASSPGLSLAKNIQYF at positions 5–7; Figure 6B and Table 3) were similar to the PGLAG motif of the consensus sequence identified from HLA-A*0201–restricted Tax11-19–specific CD8+ T cells in the peripheral blood of HLA-A*0201+ HAM/TSP patients (Figure 5C). Here, CD8A is linked to tropical spastic paraparesis.