AKT1 and metabolic syndrome: This preventing effect is a result of substantially elevated levels of expression of proteins contributing to lipolysis or lipogenesis, along with Akt and hepatic AMPK.53 In line with this notion, an in vivo study documented a reversing effect of Lactobacillus johnsonii N6.2 supplementation on the hyperactivation of mTORC1-activating phosphorylation of pAkt in high-fat diet-fed regime and the reduction of metabolic syndrome-associated changes.59