The study of Seo et al. showed that protein isoforms of MFF, a molecule that controls mitochondrial size and shape, were overexpressed in patients with NSCLC and formed homo- and heterodimeric complexes with voltage-dependent anion channel-1 (VDAC1), a key regulator of mitochondrial outer membrane permeability [124]. This evidence concerns the gene MFF and non-small cell lung carcinoma.