The levels of DISC-1 and TDP-43, 2 molecules related to schizophrenia and amyotrophic lateral sclerosis–frontal temporal dementia (see Table 1) were unchanged in both hippocampal and neocortical tissues of Ndel1 CKO mice when compared with those of WT littermates. The gene discussed is TARDBP; the disease is amyotrophic lateral sclerosis.