Previous studies showed that while the non‐Sia‐binding Siglec‐XII can be expressed in SIGLEC12 mutated PC‐3 human prostate cancer cells, efforts to transfect the chimpanzee version of SIGLEC12 or the arginine‐restored version of human SIGLEC12 were not successful.11 This evidence concerns the gene SIGLEC12 and prostate cancer.