FSCN1 and cancer: The overexpression of FSCN1 in breast (MDA-MB-435 and MDA-MB-231),73 cholangiocarcinoma (REB),123 esophageal (SHEE),88 lung (SPC-A-1, H1229),102,107 or oral (AW13516)128 cancer cell lines was found to enhance cell proliferation rates (Table 2).