However, FSCN1 knockdown did not exhibit any effect on cell proliferation in multiple cancer cell lines, including bladder cancer (5637 and BIU87),70 chondrosarcoma (JJ012 and SW1353),80 hepatocellular carcinoma (HLE),100 lung cancer (H1650),65 melanoma (BLM, FM3P, and WM793),103 and oral cancer (SSC-15 and HSC-3)111 cell lines. The gene discussed is FSCN1; the disease is hepatocellular carcinoma.