NPPB and hydrops fetalis: - NYHA IV, frequent hospitalizations for HF - VO2 peak ≤ 10 ml/kg/min - NT-proBNP >10.000 pg/ml - MV area <3 cm2 - Disproportionate LV disease - EROA/LVEDV ratio ≤ 0.12 - Mobile length of PL <6 mm - Coaptation depth ≥ 11 mm - Tenting area >2 cm2 - RV dysfunction without contractile reserve - Irreversible precapillary PH - MIS >30%