Many studies have shown that CKAP4 has been related to various cancers including bladder cancer, cervical carcinoma, lung cancer, cholangiocarcinoma, hepatocellular carcinoma, esophageal squamous cell carcinoma, pancreatic cancer, glioma, clear cell renal cell carcinoma, and so on. Here, CKAP4 is linked to familial pancreatic carcinoma.