Palmitoyl acyltransferase DHHC2, which is a putative tumor suppressor, modifies Cys100 of CKAP4 (Schweizer et al., 1993b; Zhang et al., 2008) and contributes to the localization of CKAP4 on the plasma membrane (Planey et al., 2009). This evidence concerns the gene ZDHHC2 and neoplasm.