Additionally, CDR1as is implicated in Alzheimer’s disease by binding to miR-7, thereby reducing the ability of miR-7 to regulate ubiquitin-conjugating enzyme E2 A (UBE2A), a protein that decreases rapidly in Alzheimer’s disease (AD) and other neurological diseases (Akhter, 2018). Here, UBE2A is linked to early-onset autosomal dominant Alzheimer disease.