Friend leukemia virus integration 1 (FLI1), an ETS transcription factor family member that acts as an oncogenic driver in hematological malignancies was found to enhance the invasiveness of breast cancer cells (MDA-MDB 231) by binding to the FLI1 promoter and recruiting TET1 (demethylase), thereby regulating DNA demethylation (Chen N. et al., 2018). The gene discussed is FLI1; the disease is breast carcinoma.