MMP11 and cancer: 1 MiR-139 level was down-regulated in tumors compared with adjcent normal tissues2 Exosomal miR-139 in CAFs was reduced compared to NFs3 Exosomes shuttled miR-139 from fibroblasts to cancer cells4 MiR-139 overexpression in CAFs suppressed cancer cells growth and metastasis by inhibiting the expression of MMP11