1 miR-320a level was reduced in CAFs-derived exosomes compared to NFs2 Fibroblasts derived exosomal miR-320a could transfer to HCC cells3 Exosomal miR-320a binded to PBX3 in HCC cells and inhibited their proliferation and metastasis.4 MiR-320a-PBX3 axis suppressed tumor progression by inhibiting MAPK pathway acitivation. Here, PBX3 is linked to neoplasm.