The mRNA levels and expression of cofilin were significantly increased in tumor tissues than in benign prostatic hyperplasia tissues or normal tissues, this was a common phenomenon that observed in various types of cancer, such as hepatoblastoma (Liu et al., 2018), breast cancer (Maimaiti et al., 2017), non-small cell lung cancer (Wei et al., 2012), prostate cancer (Collazo et al., 2014; Lu et al., 2015), colorectal cancer (Sousa-Squiavinato et al., 2019), vulvar squamous cell carcinoma (Wu et al., 2016), ovarian cancer (Chen et al., 2014), and bladder cancer (Wang et al., 2017). Here, CFL1 is linked to breast carcinoma.