Casadesus et al. (2007) described that increased LH levels are associated with declines in cognitive performance. Human chorionic gonadotrophin (hCG), which shares the α-subunit with LH and acts through the same LHR receptor (Choi and Smitz, 2014), increases gastric cancer cell proliferation through the PKA/c-Met signaling pathway (Zhao et al., 2018). Regarding LHR, its overexpression in endometrial cancer cells increases invasiveness, tumor development, and distal metastasis (Pillozzi et al., 2013). The gene discussed is MET; the disease is endometrial cancer.