So far, Cxcl10, Myc, Timp1, Serpina3n, and Ednrb have been reported to be upregulated in retinas after light damage (Rattner and Nathans, 2005; Rutar et al., 2015; Mansouri et al., 2020) or other injury/diseases models such as retinal detachment (Rattner and Nathans, 2005), glaucoma (Naskar and Thanos, 2006), or retinal ischemia-reperfusion (Abcouwer et al., 2013). The gene discussed is EDNRB; the disease is glaucoma.