We analyzed the CFI expression profile across diverse tumors in TCGA database and found that CFI was significantly overexpressed in COAD (colon adenocarcinoma), GBM, LGG, READ (rectum adenocarcinoma), STAD (stomach adenocarcinoma), and THCA (thyroid carcinoma) relative to the corresponding normal samples (Figure 1A). Here, CFI is linked to rectum adenocarcinoma.