As shown in Supplementary Table 1, JAK/STAT, NOD-like receptor, pathways in cancer, T cell receptor, and vascular endothelial growth factor (VEGF) were significantly enriched in the CFIhigh gliomas (Supplementary Figure 2) and therefore may be involved in mechanisms underlying CFI upregulation in glioma. Here, SOAT1 is linked to central nervous system cancer.