AKT1 and non-small cell lung carcinoma: Likewise, according to numerous current investigations, the chemosensitivity of NSCLC cells to DDP could be increased through the inactivation of the PI3K/Akt pathway (Chen et al., 2017; Shi et al., 2017; Gong et al., 2018; Liu et al., 2018; Xia et al., 2018; Zhao et al., 2018).