Among the experimental mouse strains tested, B10.RIII is the most highly susceptible to experimental autoimmune uveitis (EAU) induced by active immunization with the retinal antigen, interphotoreceptor retinoid binding protein (IRBP), without need for additional stimulation with pertussis toxin (Horai and Caspi, 2010). Here, RBP3 is linked to autoimmune uveitis.