MBP and myeloid sarcoma: Human gut flora inoculated into GF MBP TCR transgenic mice was able to support spontaneous EAE development (Berer et al., 2017; Cekanaviciute et al., 2017) and microbial candidates (Akkermansia muciniphila and Acinetobacter calcoaceticus) that were enriched in MS patients induced proinflammatory responses in human peripheral blood mononuclear cells and in mono-colonized mice (Cekanaviciute et al., 2017).