It has been reported previously that if cancer cells metastasize, they must be detached from original tissues firstly and bind with proteins (24), while “intracellular protein transport” contributes to gaining specific proteins for cancer cells; there are also some studies documented that “regulation of autophagy”, “DNA damage response”, and “signal transduction by p53 class mediator resulting in cell cycle arrest” play significant roles in cancer metastasis (25). The gene discussed is TP53; the disease is cancer.