MYCNOS and cancer: This might be related to the N-MYC-independent functions of NCYM, e.g., NCYM-mediated inhibition of GSK3β also lead to the stabilization of β-catenin, which promotes bladder cancer progression (138); NCYM promotes generation of MYC-nicks, cytoplasmic cleavage products of N-MYC and C-MYC, which inhibits apoptosis and enhances cancer cell migration (139).