Among these 30 ARGs, 8 ARGs were up-regulated (FAS, ATG16L2, WDR45, FOXO1, HIF1A, ATG4C, CTSD, and EEF2K) and 22 were down-regulated (HGS, EIF4EBP1, EDEM1, RGS19, CXCR4, IKBKB, EIF4G1, BAK1, MYC, CAPN1, CAPN2, ZFYVE1, GAA, SPNS1, EEF2, ATG5, DAPK1, CASP1, ATG7, RELA, CLN3, and ULK3) in patients with MDS (Figure 1B). This evidence concerns the gene CASP1 and myelodysplastic syndrome.