Among these 30 ARGs, 8 ARGs were up-regulated (FAS, ATG16L2, WDR45, FOXO1, HIF1A, ATG4C, CTSD, and EEF2K) and 22 were down-regulated (HGS, EIF4EBP1, EDEM1, RGS19, CXCR4, IKBKB, EIF4G1, BAK1, MYC, CAPN1, CAPN2, ZFYVE1, GAA, SPNS1, EEF2, ATG5, DAPK1, CASP1, ATG7, RELA, CLN3, and ULK3) in patients with MDS (Figure 1B). Here, CLN3 is linked to myelodysplastic syndrome.