Among these 30 ARGs, 8 ARGs were up-regulated (FAS, ATG16L2, WDR45, FOXO1, HIF1A, ATG4C, CTSD, and EEF2K) and 22 were down-regulated (HGS, EIF4EBP1, EDEM1, RGS19, CXCR4, IKBKB, EIF4G1, BAK1, MYC, CAPN1, CAPN2, ZFYVE1, GAA, SPNS1, EEF2, ATG5, DAPK1, CASP1, ATG7, RELA, CLN3, and ULK3) in patients with MDS (Figure 1B). The gene discussed is WDR45; the disease is myelodysplastic syndrome.