TNF and myelodysplastic syndrome: In addition, KEGG enrichment showed that the DEGs in MDS are primarily involved in the TNF signaling pathway, PI3K-Akt signaling pathway, p53 signaling pathway, NOD-like receptor signaling pathway, NF-kappa B signaling pathway, MAPK signaling pathway, Chronic myeloid leukemia, autophagy-animal signaling pathway, apoptosis signaling pathway, and AGE-RAGE signaling pathway, among others.