Among these 30 ARGs, 8 ARGs were up-regulated (FAS, ATG16L2, WDR45, FOXO1, HIF1A, ATG4C, CTSD, and EEF2K) and 22 were down-regulated (HGS, EIF4EBP1, EDEM1, RGS19, CXCR4, IKBKB, EIF4G1, BAK1, MYC, CAPN1, CAPN2, ZFYVE1, GAA, SPNS1, EEF2, ATG5, DAPK1, CASP1, ATG7, RELA, CLN3, and ULK3) in patients with MDS (Figure 1B). This evidence concerns the gene ATG16L2 and myelodysplastic syndrome.