Immune cells including dendritic cell (DC), NK cell, myeloid-derived suppressor cell (MDSC), CD8+ T cell, CD4 +T cell, regulatory T cell (Treg), T helper cell 1 (Th1), T helper cell 2 (Th2), T helper cell 17 (Th17), and tumor-associated macrophages (TAMs) (177–179). Here, CD4 is linked to neoplasm.