AKT1 and neoplasm: The specific mechanisms of lncRNAs regulating autophagy can be divided into three categories: lncRNAs act as competitive endogenous RNAs (ceRNAs) combined with miRNAs to regulate the expression of miRNAs, thus affecting the process of autophagy (28); lncRNAs can also affect the expression of ATG gene cis or trans (24); lncRNAs promote tumor progression by inhibiting autophagy-mediated apoptosis through AKT/mTOR pathway (29).